Volume 19 • Number 1 January 2014

EDITORIAL

The Thorough QT Study: Is Its Demise on the Horizon?

Philip T. Sager and Peter Kowey

 

REVIEW ARTICLES

ECG Diagnosis and Classification of Acute Coronary Syndromes

Yochai Birnbaum, James Michael Wilson, Miquel Fiol, Antonio Bayes de Luna, Markku Eskola,

and Kjell Nikus

 

Early Repolarization Syndrome: Electrocardiographic Signs and Clinical

Implications

Ciprian Rezus, Mariana Floria, Victor Dan Moga, Oana Sirbu, Nicoleta Dima, Simona Daniela Ionescu,

and Valentin Ambarus

 

ORIGINAL ARTICLES

Heart Rate Variability and Procedural Outcome in Catheter Ablation for

Atrial Fibrillation

Geoffrey E.J. Seaborn, Keith Todd, Kevin A. Michael, Adrian Baranchuk, Hoshiar Abdollah,

Christopher S. Simpson, Selim G. Akl, and Damian P. Redfearn

 

Electrocardiographic Reference Values for a Population of Older Adults

in Sub-Saharan Africa

Matthew J. Dewhurst, Luigi Y. Di Marco, Felicity Dewhurst, Philip C. Adams, Alan Murray,

Golda P. Orega, Julius C. Mwita, Richard W. Walker, and Philip Langley

 

Fragmented Surface ECG Was a Poor Predictor of Appropriate Therapies in Patients

with Chagas’ Cardiomyopathy and ICD Implantation (Fragmented ECG in CHAgas’

Cardiomyopathy Study)

Adrian Baranchuk, Francisco Femenia, Juan Cruz Lopez-Diez, Claudio Muratore, Mariana Valentino,

Enrique Retyk, Nestor Galizio, Darıo Di Toro, Karina Alonso, Wilma M. Hopman, and Rodrigo Miranda

on behalf of the FECHA Study Investigators

 

Celecoxib-Induced Change in Atrial Electrophysiologic Substrate in Arthritis

Patients

Katerina Pizzuto, Henry L Averns, Adrian Baranchuk, Hoshiar Abdollah, Kevin A. Michael,

Christopher Simpson, and Damian P. Redfearn

 

P-Wave Abnormality Predicts Recurrence of Atrial Fibrillation after Electrical

Cardioversion: A Prospective Study

Hanney Gonna, Mark Michael Gallagher, Xiao Hua Guo, Yee Guan Yap, Katerina Hnatkova,

and A. John Camm  

 

HEREDITARY ARRHYTHMIA CORNER

Single Nucleotide Polymorphisms in Proximity to K-Channel Genes Are Associated

with Decreased Longitudinal QTc Variance

Yuliya Mints, Vadim Zipunnikov, Irfan Khurram, Hugh Calkins, and Saman Nazarian

CARDIAC SAFETY

The IQ-CSRC Prospective Clinical Phase 1 Study: “Can Early QT Assessment Using

Exposure Response Analysis Replace the Thorough QT Study?”

Borje Darpo, Nenad Sarapa, Christine Garnett, Charles Benson, Corina Dota, Georg Ferber,

Venkateswar Jarugula, Lars Johannesen, James Keirns, Kevin Krudys, Catherine Ortemann-Renon,

Steve Riley, Danise Rogers-Subramaniam, and Norman Stockbridge

 

Use of Continuous ECG for Improvements in Assessing the Standing Response

as a Positive Control for QT Prolongation

Anthony A. Fossa, Meijian Zhou, Nuala Brennan, Patrick Round, and John Ford

 

CASE REPORTS

Bidirectional Ventricular Tachycardia?

Jos´e L. Serra, Julian A. Caresani, and Julio O. Bono

 

Very Early Recurrence of Takotsubo Syndrome

Zhaolong Xu, Qiang Li, Renguang Liu, and Yuhong Li

 

Vagal Enhancement Linking Abnormal Blood Pressure Response and Subendocardial

Ischemia in Hypertrophic Cardiomyopathy

Tatsuya Kawasaki and Hiroki Sugihara

 

LETTER TO THE EDITOR

T-Wave Alternans, ST-Segment Depression, Left Ventricular Hypertrophy, and

Mortality Risk in Patients with Ischemic Cardiomyopathy: Some Possible

Confounding Factors

John E. Madias

 

Volume 19 • Number 2 March 2014

REVIEW ARTICLE

Noninvasive Imaging of Cardiac Excitation: Current Status and Future Perspective

A.W. Maurits van der Graaf, Pranav Bhagirath, Hemanth Ramanna, Vincent J.H.M. van Driel,

Jacques de Hooge, Natasja M.S. de Groot, and Marco J.W. Gotte

 

ORIGINAL ARTICLES

Number of P-Wave Fragmentations on P-SAECG Correlates with Infiltrated Atrial

Fat

Sindhoora Murthy, Patricia Rizzi, Nathan Mewton, David G. Strauss, Chia Y. Liu,

Gustavo Jardim Volpe, Francis E. Marchlinski, Peter Spooner, Ronald D. Berger, Peter Kellman,

Joao A.C. Lima, and Larisa G. Tereshchenko

 

Automated Assessment of Cardiac Autonomic Function by Means of Deceleration

Capacity from Noisy, Nonstationary ECG Signals: Validation Study

Christian Eick, Konstantinos D. Rizas, Christine S. Zuern, and Axel Bauer

 

Diagnostic Accuracy of a New Cardiac Electrical Biomarker for Detection of

Electrocardiogram Changes Suggestive of Acute Myocardial Ischemic Injury

David M. Schreck and Robert D. Fishberg

 

An Analysis of the U-Wave and Its Relation to the T-Wave in Body Surface Potential

Maps for Healthy Subjects and MI Patients

Małgorzata Fereniec, Gunter Stix, Michał Kania, Tomasz Mroczka, and Roman Maniewski

 

Heart Rate Variability and Heart Rate Turbulence in Patients with Hematologic

Malignancies Subjected to High-Dose Chemotherapy in the Course of

Hematopoietic Stem Cell Transplantation

Małgorzata Poreba, Rafał Poreba, Paweł Ga´c, Lidia Usnarska-Zubkiewicz, Witold Pilecki,

Ewa Piotrowicz, Ryszard Piotrowicz, Leszek Rusiecki, Kazimierz Kuliczkowski, Grzegorz Mazur,

and Małgorzata Sobieszczanska

 

Relation of Low Vitamin D to Nonvalvular Persistent Atrial Fibrillation in Chinese

Patients

Wei Ren Chen, Zhi Ying Liu, Yang Shi, Da Wei Yin, Hao Wang, Yuan Sha, and Yun Dai Chen

 

Holter Electrocardiography Findings and P-Wave Dispersion in Pediatric Patients

with Transcatheter Closure of Atrial Septal Defects

Isa Ozyilmaz, Sinem Ozyilmaz, Hasan Tahsin Tola, Murat Saygi, Neslihan Kiplapinar,

Cansaran Tanıdır, Yakup Ergul, Alper Guzeltas, and Ender Odemis

 

CARDIAC SAFETY

Comparison of Two Methods of Estimating Reader Variability in QT Interval

Measurements in Thorough QT/QTc Studies

Vaibhav Salvi, Dilip R. Karnad, Vaibhav Kerkar, Gopi Krishna Panicker, Mili Natekar,

and Snehal Kothari

 

CASE REPORTS

QT Prolongation and T-Wave Alternans during Catheter Ablation of Atrial

Fibrillation: A Case Report

Aditya Saini, Hemal Shah, and Samir Saba

 

Sustained Ventricular Tachycardia in a Patient with Thalassemia Major

Nermin Bayar, Sakir Arslan, Zehra Erkal, and Selcuk Kucukseymen

 

EKG Pattern of Brugada Syndrome and Sudden Infant Death Syndrome—Is It Time

to Review the Diagnostic Criteria? Case Report and Review of Literature

Emiliana Franco, Andre Dias, Daniele Teresa, and Kathy Hebert

 

LETTER TO THE EDITOR

Is Prolonged QTc Sufficient to Predict Survival in Patients with Intracerebral

Hemorrhage?

Yavuzer Koza

 

Response to Koza

Is Prolonged QTc Sufficient to Predict Survival in Patients with Intracerebral

Hemorrhage?

Clara Hjalmarsson and Lennart Bergfeldt

Volume 19 • Number 3 May 2014 

REVIEW ARTICLE

Interaction between Heart Rate and Heart Rate Variability

Jerzy Sacha

 

ORIGINAL ARTICLES

A Novel Method for Real-Time Atrial Fibrillation Detection in Electrocardiograms

Using Multiple Parameters

Xiaochuan Du, Nini Rao, Mengyao Qian, Dingyu Liu, Jie Li, Wei Feng, Lixue Yin,

and Xu Chen

 

Impact of Continuous Positive Airway Pressure Therapy on Atrial

Electromechanical Delay and P-Wave Dispersion in Patients with Obstructive

Sleep Apnea

Pınar Turker Bayır, Burcu Demirkan, Omer Bayır, Serkan Duyuler, Hikmet Fırat, Umit Guray,

Yesim Guray, and Emel Cadallı Tatar

 

Electrocardiographic Findings in Accessory Right Precordial Leads in Adults and

Seniors with Notched S Waves in Lead V1—A Preliminary Study

Zhan Zhong-qun, Kjell C. Nikus, Andres Ricardo Perez-Riera, and Wang Chong-quan

 

Brief Assessment of Supine Heart Rate Variability in Normal Weight, Overweight,

and Obese Females

Zienab Alrefaie

 

Sudden Cardiac Arrest in Hemodialysis Patients with Wearable Cardioverter

Defibrillator

Chingping Wan, Charles A. Herzog, Wojciech Zareba, and Steven J. Szymkiewicz

 

Electrocardiography at Diagnosis and Close to the Time of Death in Pulmonary

Arterial Hypertension

Adriano R. Tonelli, Manfred Baumgartner, Laith Alkukhun, Omar A. Minai,

and Raed A. Dweik

 

Usefulness of P-Wave Signal Averaging to Predict Atrial Fibrillation Recurrences

after Electrical Cardioversion

Coralie Blanche, Nam Tran, David Carballo, Fabio Rigamonti, Haran Burri,

and Marc Zimmermann

 

Nonreassuring Fetal Heart Rate Decreases Heart Rate Variability in Newborn

Infants

Tzong-Chyi Sheen, Ming-Huei Lu, Mei-Yu Lee, and Su-Ru Chen

 

CASE REPORTS

The Use of Fontaine Leads in the Diagnosis of Arrhythmogenic Right Ventricular

Dysplasia

Byron Gottschalk, Michael Gysel, Raimundo Barbosa-Barros, Ricardo Paulo De Sousa Rocha,

Andres Ricardo Perez-Riera, Li Zhang, Guy Fontaine, and Adrian Baranchuk

 

Reversible T-Wave Inversions and Neurogenic Myocardial Stunning in a Patient with

Recurrent Stress-Induced Cardiomyopathy

Yasushi Akutsu, Kyouichi Kaneko, Yusuke Kodama, Hui-Ling Li, Jumpei Suyama, Tsutomu Toshida,

Hiroyuki Kayano, Akira Shinozuka, Takehiko Gokan, and Youichi Kobayashi

 

Wide Complex Tachycardia in the Presence of Class I Antiarrhythmic Agents:

A Diagnostic Challenge

Bhaskar Bhardwaj, Ralph Lazzara, and Stavros Stavrakis

 

Sudden Death Due to Nonarrhythmic Cause in a Patient with L-TGA

Robert M. Hayward, Philip C. Ursell, Elyse Foster, and Zian H. Tseng

 

Volume 19 • Number 4 July 2014

REVIEW ARTICLES

Vernakalant for the Conversion of Atrial Fibrillation: The New Kid On the Block?

Diego Conde and Adrian Baranchuk

 

Beneficial Effects of Physical Activity on Baroreflex Control in the Elderly

Maria Teresa La Rovere and Gian Domenico Pinna

 

Utility of the Exercise Electrocardiogram Testing in Sudden Cardiac Death Risk

Stratification

Marwan M. Refaat, Mostafa Hotait, and Zian H. Tseng

 

ORIGINAL ARTICLES

Reliability and Validity of Clinician ECG Interpretation for Athletes

Charles Magee, Joshua Kazman, Mark Haigney, Ralph Oriscello, Kent J. DeZee, Patricia Deuster,

Patrick Depenbrock, and Francis G. O’Connor

 

A Novel ECG-Index for Prediction of Ventricular Arrhythmias in Patients after

Myocardial Infarction

Mathias Hetland, Kristina H. Haugaa, Sebastian I. Sarvari, Gunnar Erikssen, Erik Kongsgaard,

and Thor Edvardsen

 

Significance and Usefulness of Narrow Fragmented QRS Complex on 12-Lead

Electrocardiogram in Acute ST-Segment Elevation Myocardial Infarction for

Prediction of Early Mortality and Morbidity

Berna Stavileci, Murat Cimci, Baris Ikitimur, Hasan Ali Barman, Sevgi Ozcan, Esra Ataoglu,

and Rasim Enar

 

Ranolazine for the Suppression of Ventricular Arrhythmia: A Case Series

Eric Yeung, Mori J. Krantz, Joseph L. Schuller, Rita A. Dale, and Mark C. Haigney

 

Fragmented QRS Predicts the Arrhythmic Events in Patients with Heart Failure

Undergoing ICD Implantation for Primary Prophylaxis: More Fragments More

Appropriate ICD Shocks

Fırat Ozcan, Osman Turak, Ugur Canpolat, Sedat Avci, Derya Tok, Ahmet Isleyen,

Muhammed Cebeci, Huseyin Yuzgecer, Ozgu¨ l Malcok Gurel, Serkan Topaloglu, Dursun Aras,

Fatma Nurcan Basar, and Sinan Aydogdu

 

QT Restitution Properties during Exercise in Male Patients with Coronary Artery

Disease

Dongdong Zhao, Yidong Wei, Kai Tang, Xuejing Yu, Jing Wen, Jingying Zhang, and Yawei Xu

 

P-Wave Morphology Is Unaffected by Atrial Size: A Study in Healthy Athletes

Richard Petersson, Hilde M. Berge, Gard F. Gjerdalen, Jonas Carlson, Fredrik Holmqvist,

Kjetil Steine, and Pyotr G. Platonov

 

Assessment of Inhomogeneities of Repolarization in Patients with Systemic Lupus

Erythematosus

Ahmet Avci, Kenan Demir, Bulent Behlul Altunkeser, Sema Yilmaz, Ahmet Yilmaz,

Ahmet Ersecgin, and Tarik Demir

 

GENETIC CORNER

Effect of Flecainide on T-Wave Alternans in Andersen–Tawil Syndrome

Hideki Hayashi, Tamiro Kawaguchi, and Minoru Horie  

 

CASE REPORTS

Brugada Phenocopy Clinical Reproducibility Demonstrated by Recurrent

Hypokalemia

Natalia R. Genaro, Daniel D. Anselm, Nahuel Cervino, Ariel O. Estevez, Carlos Perona,

Alejandro M. Villamil, Ruben Kervorkian, and Adrian Baranchuk

 

Sinus Arrest and Asystole Caused by a Peripherally Inserted Central Catheter

Allison Nazinitsky, Melody Covington, and Laszlo Littmann

 

Unusual Cause of Syncope in a Patient with Ischemic Heart Disease

Mohit D. Gupta, Girish, Mayank Goyal, MSK Subhendu, and Sanjay Tyagi

 

Correlation Between ST-Segment Elevation and Negative T Waves in the Precordial

Leads in Acute Pulmonary Embolism: Insights into Serial Electrocardiogram

Changes

Zhan Zhong-qun, Yang Bo, Kjell C. Nikus, Andres Ricardo Perez-Riera, Wang Chong-quan,

and Wang Xian-ming

 

LETTERS TO THE EDITOR

P-Wave Duration or P-Wave Morphology? Interatrial Block: Seeking for the Holy

Grail to Predict AF Recurrence

Adrian Baranchuk, Diego Conde, Andres Enriquez, and Antoni Bayes de Luna

 

Response to Baranchuk et al.

Hanney Gonna and Mark M Gallagher

 

Volume 19 • Number 5 September 2014 

INTRODUCTION

Consensus Documents on Current Topics in ECG Interpretation

Wojciech Zareba, Ryszard Piotrowicz, Miguel Fiol, and Antoni Bayes de Luna

 

REVIEW ARTICLES

The Role of the ECG in Diagnosis, Risk Estimation, and Catheterization Laboratory

Activation in Patients with Acute Coronary Syndromes: A Consensus Document

Yochai Birnbaum, Kjell Nikus, Paul Kligfield, Miguel Fiol, Jose Antonio Barrabes, Alessandro Sionis,

Olle Pahlm, J. Garcia Niebla, and Antonio Bayes de Luna

 

Negative T Wave in Ischemic Heart Disease: A Consensus Article

Antonio Bayes de Luna, Wojciech Zareba, Miquel Fiol, Kjell Nikus, Yochai Birnbaum,

Rafael Baranowski, Diego Goldwasser, Paul Kligfield, Ryszard Piotrowicz, Gunter Breithardt,

and Hein Wellens

 

Prinzmetal Angina: ECG Changes and Clinical Considerations: A Consensus Paper

Antonio Bayes de Luna, Iwona Cygankiewicz, Adrian Baranchuk, Miquel Fiol, Yochai Birnbaum,

Kjell Nikus, Diego Goldwasser, Javier Garcia-Niebla, Samuel Sclarovsky, Hein Wellens,

and Gunter Breithardt

 

ORIGINAL ARTICLES

Myocardial Tissue Perfusion Predicts the Evolution of Fragmented QRS in Patients

with ST-Segment Elevation Myocardial Infarction Undergoing Primary

Percutaneous Coronary Intervention

Firat Ozcan, Osman Turak, Ugur Canpolat, Iskender Kadife, Sedat Avci, Ahmet Isleyen,

Muhammed Cebeci, Ozgu¨ l Malcok Gurel, Fatma Nurcan Basar, Derya Tok, Serkan Topaloglu,

Dursun Aras, and Sinan Aydogdu

 

Comparison of Cardiogoniometry and ECG at Rest versus Myocardial Perfusion

Scintigraphy

Stefan Weber, Ralf Birkemeyer, Dominik Schultes, Walter Grewenig, and Thomas Huebner

 

Influence of Atrioventricular Optimization on Hemodynamic Parameters and Quality

of Life in Patients with Dual Chamber Pacemaker with Ventricular Lead in Right

Ventricular Outflow Tract

Artur Klimczak, Adam S. Budzikowski, Marcin Rosiak, Marzenna Zielinska, Bozena Urbanek,

Karol Bartczak, Michał Chudzik, and Jerzy K. Wranicz

 

Parameters of Heart Rate Variability Can Predict Prolonged Asystole before Head-Up

Tilt Table Test

Erdal Gursul, Serdar Bayata, Selcen Yakar Tuluce, Rida Berilgen, Ozgen Safak, Emre Ozdemir,

and Kamil Tuluce

 

The Natural History of Multifocal Atrial Rhythms in Elderly Outpatients: Insights

from the “Ikaria Study”

George Lazaros, Christina Chrysohoou, Evaggelos Oikonomou, Dimitrios Tsiachris, Savvas Mazaris,

Erifili Venieri, Kostas Zisimos, Marina Zaromytidou, Maria Kariori, Stamatis Kioufis, Christos Pitsavos,

and Christodoulos Stefanadis

 

Short QT in a Cohort of 1.7 Million Persons: Prevalence, Correlates, and Prognosis

Carlos Iribarren, Alfred D. Round, Jonathan A. Peng, Meng Lu, Arthur L. Klatsky, Jonathan G. Zaroff,

Taylor J. Holve, Amit Prasad, and Paul Stang

 

CASE REPORTS

A New Type of Dual Atrioventricular Nodal Nonreentrant Tachycardia

Krzysztof Kaczmarek, Jan Ruta, Jerzy Wranicz, and Pawel Ptaszynski

 

Coexistence of Wolff–Parkinson–White and Brugada Syndrome: Mere Curiosity?

Elisabeth Kaiser, Luciana Sacilotto, Francisco Darrieux, and Eduardo Sosa

 

LETTER TO THE EDITOR

LMCA Disease and T-Wave Positivity in Lead aVR

Nihal Tefik and Atila Bitigen

 

Volume 19 • Number 6 November 2014 

REVIEW ARTICLES

Correlation of Electrocardiogram and Regional Cardiac Magnetic Resonance Imaging

Findings in ST-Elevation Myocardial Infarction: A Literature Review

Irina Rinta-Kiikka, Suvi Tuohinen, Pertti Ryymin, Petteri Kosonen, Heini Huhtala,

Anton Gorgels, Antonio Bayes de Luna, and Kjell Nikus

 

Left Ventricular Hypertrophy: The Relationship between the Electrocardiogram and

Cardiovascular Magnetic Resonance Imaging

Ljuba Bacharova and Martin Ugander

 

QRS-T Angle: A Review

Andrew Oehler, Trevor Feldman, Charles A. Henrikson, and Larisa G. Tereshchenko

 

ORIGINAL ARTICLES

Electrocardiogram Patterns during Hemodynamic Instability in Patients with Acute

Pulmonary Embolism

Zhong-qun Zhan, Chong-quan Wang, Kjell C. Nikus, Chao-rong He, Jin Wang, Shan Mao,

and Xiong-jian Dong

 

Relationship of Electrocardiographic Left Ventricular Hypertrophy to the Presence of

Diastolic Dysfunction

Joseph M. Krepp, Fay Lin, James K. Min, Richard B. Devereux, and Peter M. Okin 

 

QT Dispersion in HIV-Infected Patients Receiving Combined Antiretroviral

Therapy

Wanwarang Wongcharoen, Somkhuan Suaklin, Nualnit Tantisirivit, Arintaya Phrommintikul,

and Nipon Chattipakorn

 

Evolution of Electrocardiographic Abnormalities in Association with Neuromuscular

Disorders and Survival in Left Ventricular Hypertrabeculation/Noncompaction

Claudia Stollberger, Daniel Gerger, Peter Jirak, Christian Wegner, and Josef Finsterer

 

QT Interval Prolongation in End-Stage Liver Disease Cannot Be Explained by

Nonhepatic Factors

Divyang Patel, Prabhpreet Singh, William Katz, Christopher Hughes, Kapil Chopra,

and Jan Nemec

 

CARDIAC SAFETY

Use of ECG Restitution (Beat-to-Beat QT-TQ Interval Analysis) to Assess

Arrhythmogenic Risk of QTc Prolongation with Guanfacine

Anthony A. Fossa, Meijian Zhou, Antoine Robinson, Jaideep Purkayastha, and Patrick Martin

 

CASE REPORTS

Asystole Detected by Implantable Loop Recorders: True or False?

Hussam Ali, Antonio Sorgente, Elisabetta Daleffe, and Riccardo Cappato

Piezoelectric Electrocardiographic Artifact in a Patient after Surgery with

Bradycardia and Hypotension

Richard Cheng and Tarun Chakravarty

 

U Wave Variability in the Surface ECG

Piotr Kukla, Adrian Baranchuk, Marek Jastrzebski, and Leszek Bryniarski

 

LETTERS TO THE EDITOR

Brugada Phenocopy: Morphological Classification and Importance of Provocative

Testing

Byron Gottschalk, Daniel D. Anselm, and Adrian Baranchuk

Response to: Brugada Phenocopy: Morphological Classification and Importance of

Provocative Testing

Mehdi Rambod, Sherif Elhanafi, and Debabrata Mukherjee